{"id":1677,"date":"2022-08-14T09:16:25","date_gmt":"2022-08-14T07:16:25","guid":{"rendered":"https:\/\/www.diagnostic-mental.fr\/blog\/?p=1677"},"modified":"2022-08-14T09:16:25","modified_gmt":"2022-08-14T07:16:25","slug":"lage-du-pere-est-lie-au-risque-dautisme-de-lenfant","status":"publish","type":"post","link":"https:\/\/www.diagnostic-mental.fr\/blog\/autisme\/lage-du-pere-est-lie-au-risque-dautisme-de-lenfant\/","title":{"rendered":"L’\u00e2ge du p\u00e8re est li\u00e9 au risque d’autisme de l’enfant"},"content":{"rendered":"

C’est l’\u00e2ge du p\u00e8re, et non celui de la m\u00e8re, qui est un facteur d’augmentation du risque d’autisme<\/a> chez l’enfant. En effet, le nombre de mutations g\u00e9n\u00e9tiques dans le sperme augmente avec l’\u00e2ge, selon une \u00e9tude publi\u00e9e dans la revue Nature<\/span>.<\/p><\/blockquote>\n

Comme le souligne Kari Stefansson, de l’institut deCODE Genetics \u00e0 Reykjavik, en d\u00e9pit des id\u00e9es re\u00e7ues selon lesquelles le risque de troubles du d\u00e9veloppement chez un enfant augmente avec l’\u00e2ge de la m\u00e8re, ce sont les hommes qui transmettent le plus de mutations g\u00e9n\u00e9tiques.<\/p>\n

L’\u00e9quipe de Stefansson a s\u00e9quenc\u00e9 le g\u00e9nome de 78 familles dont la prog\u00e9niture \u00e9tait atteinte de troubles du spectre autistique ou de schizophr\u00e9nie.<\/p>\n

Les chercheurs ont constat\u00e9 que plus le p\u00e8re est \u00e2g\u00e9, plus le risque de voir appara\u00eetre chez sa prog\u00e9niture des variantes g\u00e9n\u00e9tiques susceptibles d’entra\u00eener les troubles susmentionn\u00e9s est \u00e9lev\u00e9 – avec une moyenne de deux mutations ajout\u00e9es chaque ann\u00e9e. Chez les femmes, en revanche, le nombre de mutations h\u00e9rit\u00e9es par l’enfant ne d\u00e9pendait pas de l’\u00e2ge. Il convient toutefois de noter que les facteurs g\u00e9n\u00e9tiques ne peuvent expliquer qu’environ 10 % des cas d’autisme.<\/p>\n

Bien que les chercheurs ne puissent pas dire quand les hommes peuvent commencer \u00e0 s’inqui\u00e9ter de cette corr\u00e9lation (principalement en raison du grand nombre d’autres facteurs, notamment environnementaux, qui influent sur la sant\u00e9 de l’enfant), les r\u00e9sultats concordent avec ceux publi\u00e9s en avril par des chercheurs am\u00e9ricains, qui montrent que le risque que le p\u00e8re transmette des mutations nocives est quatre fois plus \u00e9lev\u00e9 que celui de la m\u00e8re.<\/p>\n

Ces derni\u00e8res d\u00e9cennies ont vu une augmentation du nombre d’enfants diagnostiqu\u00e9s avec un trouble du spectre autistique<\/strong>, en partie gr\u00e2ce \u00e0 de meilleurs outils de diagnostic et \u00e0 une plus grande sensibilisation du public. On estime que 1 enfant sur 88 aux \u00c9tats-Unis souffre de ce trouble, et 1 sur 100 en Europe.<\/p>\n

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Source :<\/p>\n

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  • https:\/\/www.medonet.pl\/zdrowie\/wiadomosci,wiek-ojca-zwiazany-z-ryzykiem-autyzmu-u-dziecka,artykul,1665992.html<\/em><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

    C’est l’\u00e2ge du p\u00e8re, et non celui de la m\u00e8re, qui est un facteur d’augmentation du risque d’autisme chez l’enfant. 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